Transient ultrasound stimulation has lasting effects on neuronal excitability
نویسندگان
چکیده
منابع مشابه
Allostatic regulation of neuronal excitability by transient ischemia.
During development and learning, a neuron actively maintains a stable state of excitability by adjusting the strength of its synaptic inputs (Turrigiano and Nelson, 2004). This homeostatic synaptic plasticity ensures that a neuron maintains a set-point spike firing rate when the overall synaptic input is increasing or decreasing (Turrigiano, 2008). Beside this homeostatic synaptic plasticity, n...
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The intrinsic excitability of neurons is known to be dynamically regulated by activity-dependent plasticity and homeostatic mechanisms. Such processes are commonly analyzed in the context of input-output functions that describe how neurons fire in response to constant levels of current. However, it is not well understood how changes of excitability as observed under static inputs translate to t...
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In experimental studies, electrical stimulation (ES) has been applied to induce neuronal activity or to disrupt pathological patterns. Nevertheless, the underlying mechanisms of these activity pattern transitions are not clear. To study these phenomena, we simulated a model of the hippocampal region CA1. The computational simulations using different amplitude levels and duration of ES revealed ...
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BACKGROUND Deep brain stimulation of the internal global pallidus (GPi) and the subthalamic nucleus (STN) has become a treatment alternative in advanced PD. Although the effects of GPi stimulation have been examined recently, little is known about STN stimulation effects on motor cortex excitability. METHODS The effects of STN stimulation were studied in eight patients with advanced PD using ...
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ژورنال
عنوان ژورنال: Brain Stimulation
سال: 2021
ISSN: 1935-861X
DOI: 10.1016/j.brs.2021.01.003